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At different times of the month these hormones are required to be higher or lower. The good news is that in a large study of pre- and perimenopausal women heavy flow was not caused by endometrial cancer. Heavy Menstrual Bleeding Can Be A Symptom Of Undiagnosed Hemophilia The Swaddle Knowing this it shouldnt come as a surprise that big life changes may affect your cycle. What causes heavy periods . Diagnosing what causes heavy periods can sometimes be difficult. Common causes of heavy periods include. An underactive thyroid gland hypothyroidism may. There are two female sex hormones that are of particularly important in the menstrual cycle. Endometrial hyperplasia which is the overgrowth and thickening of the endometrium can cause heavy period flow. During the beginning of a normal menstrual cycle a hormone called follicle stimulating hormone FSH rises which stimulates follicles eggs to mature in the ovaries. This can lead to thickening of. Other conditions that ca